A Phase 1 Ascending Dose Trial of the Safety and Tolerability of Toca 511 in Patients With Recurrent High Grade Glioma

Trial Profile

A Phase 1 Ascending Dose Trial of the Safety and Tolerability of Toca 511 in Patients With Recurrent High Grade Glioma

Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 23 Feb 2017

At a glance

  • Drugs Vocimagene amiretrorepvec-flucytosine gene therapy (Primary) ; Vocimagene amiretrorepvec-flucytosine gene therapy (Primary)
  • Indications Glioblastoma
  • Focus Adverse reactions
  • Sponsors Tocagen
  • Most Recent Events

    • 23 Feb 2017 According to a Tocagen media release, the U.S. Food and Drug Administration (FDA) has granted Toca 511 & Toca FC Breakthrough Therapy Designation for the treatment of patients with recurrent high grade glioma (HGG). Data from this study supported the application.
    • 11 Nov 2016 Planned End Date changed from 1 Jul 2016 to 1 Jul 2017.
    • 11 Nov 2016 Planned primary completion date changed from 1 Jul 2016 to 1 Jul 2017.
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