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A Phase IIa, Randomized, Double-blind (Participant and Investigator Blind, Sponsor Open), Placebo-controlled Trial to Evaluate the Safety, Tolerability, and Antiviral Activity of Oral ACH-0141625 in Combination With Pegylated Interferon Alpha-2a and Ribavirin in Two Segments, After 28 Days of Dosing and, Subsequently, After 12 Weeks of Dosing in Participants With Chronic Hepatitis C Virus Genotype 1

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Trial Profile

A Phase IIa, Randomized, Double-blind (Participant and Investigator Blind, Sponsor Open), Placebo-controlled Trial to Evaluate the Safety, Tolerability, and Antiviral Activity of Oral ACH-0141625 in Combination With Pegylated Interferon Alpha-2a and Ribavirin in Two Segments, After 28 Days of Dosing and, Subsequently, After 12 Weeks of Dosing in Participants With Chronic Hepatitis C Virus Genotype 1

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 03 Nov 2023

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At a glance

  • Drugs Sovaprevir (Primary) ; Peginterferon alfa-2a; Ribavirin
  • Indications Hepatitis C
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Achillion Pharmaceuticals; Alexion Pharmaceuticals

    • Most Recent Events

    • 15 Jan 2014 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov record.
    • 07 Aug 2012 SVR4 and SVR12 results for all patients are expected in the first quarter of 2013 according to an Achillion Pharmaceuticals media release.
    • 21 Apr 2012 Results have been presented at the 47th Annual Meeting of the European Association for the Study of the Liver (EASL 2012), according to an Achillion Pharmaceuticals media release.
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