Influence of Cytochrome P450 3A4 (CYP3A4)-Induction by St. John's Wort (SJW) on the Steady State Pharmacokinetics of Bosentan.

Trial Profile

Influence of Cytochrome P450 3A4 (CYP3A4)-Induction by St. John's Wort (SJW) on the Steady State Pharmacokinetics of Bosentan.

Completed
Phase of Trial: Phase I

Latest Information Update: 05 Jun 2017

At a glance

  • Drugs Bosentan (Primary) ; Hypericum
  • Indications Depression; Hypertension
  • Focus Pharmacokinetics
  • Most Recent Events

    • 01 Jun 2012 Status changed from recruiting to completed as reported by ClinicalTrials.gov.
    • 24 Jan 2011 Status changed from not yet recruiting to recruiting as reported by ClinicalTrials.gov.
    • 20 Dec 2010 New trial record
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