Trial Profile
A Multi-center, Double-blind, Randomized, Placebo- and Active-controlled, Parallel-group, Proof-of-concept Study to Evaluate the Efficacy, Safety, and Tolerability of 10 mg of ACT-280778 in Patients With Mild to Moderate Essential Hypertension.
Status:
Completed
Phase of Trial:
Phase II
Latest Information Update: 05 Oct 2018
Price :
$35
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At a glance
- Drugs ACT 280778 (Primary) ; Amlodipine
- Indications Essential hypertension
- Focus Proof of concept; Therapeutic Use
- Acronyms REDUCE-1
- Sponsors Actelion Pharmaceuticals
- 09 Mar 2013 Primary endpoint 'Seated-blood-pressure' has not been met.
- 09 Mar 2013 Primary endpoint 'Diastolic-blood-pressure' has not been met.
- 09 Mar 2013 Results presented at the 114th Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics.