A Multicenter, Randomized, Placebo-controlled, Double-blinded Study of the Efficacy and Safety of Lubiprostone in Subjects With Opioid-induced Bowel Dysfunction.

Trial Profile

A Multicenter, Randomized, Placebo-controlled, Double-blinded Study of the Efficacy and Safety of Lubiprostone in Subjects With Opioid-induced Bowel Dysfunction.

Completed
Phase of Trial: Phase III

Latest Information Update: 28 Aug 2017

At a glance

  • Drugs Lubiprostone (Primary)
  • Indications Constipation
  • Focus Registrational; Therapeutic Use
  • Most Recent Events

    • 28 Aug 2017 Results of post-hoc pooled analysis of this and other 5 studies published in the Digestive Diseases and Sciences.
    • 28 Apr 2015 Results published in the American Journal of Gastroenterology.
    • 23 Apr 2013 FDA approved sNDA for lubiprostone for opioid-induced constipation in adults with chronic, non-cancer pain based on results of OPAL trials and a long-term safety study, according to a media release from Sucampo Pharmaceuticals and Takeda Pharmaceuticals.
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at AsktheExpert.AdisInsight@springer.com so we can help.

Back to top