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A Phase 2 Study to Assess the Efficacy and Safety of CAL-101 in Patients With Indolent B-Cell Non-Hodgkin Lymphoma Refractory to Rituximab and Alkylating Agents

Trial Profile

A Phase 2 Study to Assess the Efficacy and Safety of CAL-101 in Patients With Indolent B-Cell Non-Hodgkin Lymphoma Refractory to Rituximab and Alkylating Agents

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 08 Nov 2021

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At a glance

  • Drugs Idelalisib (Primary)
  • Indications Chronic lymphocytic leukaemia; Follicular lymphoma; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma; Waldenstrom's macroglobulinaemia
  • Focus Therapeutic Use
  • Acronyms DELTA
  • Sponsors Gilead Sciences
  • Most Recent Events

    • 01 May 2021 Results assessing final efficacy and safety data published in the Leukemia and Lymphoma
    • 01 Apr 2021 Results of a post hoc analysis of data pooled from 2 trials (NCT01539512 and NCT01282424) assessing the degree of comorbidity burden and the impact of Idelalisib on bleeding events published in the Leukemia and Lymphoma
    • 21 Jun 2020 Results (N=408), pooled analysis of 4 studies assessing efficacy of Idelalisib in patients with indolent non Hodgkins lymphoma and CLL, presented at the 25th Congress of the European Haematology Association
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