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An Open-Label, Multicenter, Randomized, Phase 3 Study of S-1 and Cisplatin Compared with 5-FU and Cisplatin in Patients with Metastatic Diffuse Gastric Cancer Previously Untreated with Chemotherapy (TPU-S1303)

Trial Profile

An Open-Label, Multicenter, Randomized, Phase 3 Study of S-1 and Cisplatin Compared with 5-FU and Cisplatin in Patients with Metastatic Diffuse Gastric Cancer Previously Untreated with Chemotherapy (TPU-S1303)

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 09 Feb 2023

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At a glance

  • Drugs Gimeracil/oteracil/tegafur (Primary) ; Cisplatin; Fluorouracil
  • Indications Carcinoma; Gastric cancer; Oesophageal cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms DIGEST
  • Sponsors Taiho Pharmaceutical
  • Most Recent Events

    • 11 Jan 2022 This trial has been completed in Germany (End Date: 15 Aug 2014), according to European Clinical Trials Database record.
    • 02 Apr 2019 This trial has been completed in UK, according to European Clinical Trials Database.
    • 12 Sep 2017 Results of identification of patient population with longer survival by using clinical covariate model data from FLAGS and DIGEST phase III trials presented at the 42nd European Society for Medical Oncology Congress
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