A Phase I, 2-panel, Open-label, Randomized, Crossover Trial in Healthy Subjects to Investigate the Pharmacokinetic Interaction Between TMC435 and Transporter Substrates, Digoxin and Rosuvastatin.
Phase of Trial: Phase I
Latest Information Update: 29 Nov 2012
At a glance
- Drugs Digoxin; Rosuvastatin; Simeprevir
- Indications Arrhythmias; Heart failure; Hepatitis C; Hypercholesterolaemia
- Focus Pharmacokinetics
- Sponsors Janssen R&D Ireland
- 23 Dec 2011 Actual initiation date changed from Feb 2011 to Jan 2011 as reported by ClinicalTrials.gov.
- 14 Jul 2011 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.
- 21 Apr 2011 Status changed from recruiting to active, no longer recruiting as reported by ClinicalTrials.gov.