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An Open-Label, Randomised, Multi-Centre, Phase II Study to Investigate the Safety and Efficacy of AT13387, Either as Monotherapy or in Combination With Imatinib, in Patients With Unresectable and/or Metastatic Malignant GIST Whose Tumour Has Progressed Following Treatment With a Maximum of Three Tyrosine Kinase Inhibitors.

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Trial Profile

An Open-Label, Randomised, Multi-Centre, Phase II Study to Investigate the Safety and Efficacy of AT13387, Either as Monotherapy or in Combination With Imatinib, in Patients With Unresectable and/or Metastatic Malignant GIST Whose Tumour Has Progressed Following Treatment With a Maximum of Three Tyrosine Kinase Inhibitors.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 21 Jan 2020

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At a glance

  • Drugs Onalespib (Primary) ; Imatinib
  • Indications Gastrointestinal stromal tumours
  • Focus Therapeutic Use
  • Sponsors Astex Pharmaceuticals

    • Most Recent Events

    • 04 May 2016 Results published in the European Journal of Cancer
    • 09 Mar 2015 Status changed from active, no longer recruiting to completed, according to ClinicalTrials.gov record.
    • 06 May 2014 According to the ClinicalTrials.gov record, planned end date changed from 1 Aug 2013 to 1 Aug 2014.
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