A Phase 1 Study of Brentuximab Vedotin Administered Sequentially and Concurrently With Multi-Agent Chemotherapy as Front-Line Therapy in Patients With CD30-Positive Mature T-Cell and NK-Cell Neoplasms, Including Systemic Anaplastic Large Cell Lymphoma

Trial Profile

A Phase 1 Study of Brentuximab Vedotin Administered Sequentially and Concurrently With Multi-Agent Chemotherapy as Front-Line Therapy in Patients With CD30-Positive Mature T-Cell and NK-Cell Neoplasms, Including Systemic Anaplastic Large Cell Lymphoma

Completed
Phase of Trial: Phase I

Latest Information Update: 30 Jun 2017

At a glance

  • Drugs Brentuximab vedotin (Primary) ; Cyclophosphamide; Doxorubicin; Prednisone; Vincristine
  • Indications Anaplastic large cell lymphoma; Non-Hodgkin's lymphoma; Peripheral T-cell lymphoma; T cell lymphoma; T-cell leukaemia
  • Focus Adverse reactions
  • Sponsors Seattle Genetics
  • Most Recent Events

    • 27 Jun 2017 Status changed from active, no longer recruiting to completed.
    • 06 Dec 2016 Four year survival and durability results presented at the 58th Annual Meeting and Exposition of the American Society of Hematology.
    • 05 Dec 2016 According to a Seattle Genetics media release, data of four-year durability analysis were presented at the 58th American Society of Hematology (ASH) Annual Meeting and Exposition.
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