An International Randomised Controlled Trial to Establish the Effects of Low-dose rtPA and the Effects of Early Intensive Blood Pressure Lowering in Patients With Acute Ischaemic Stroke

Trial Profile

An International Randomised Controlled Trial to Establish the Effects of Low-dose rtPA and the Effects of Early Intensive Blood Pressure Lowering in Patients With Acute Ischaemic Stroke

Recruiting
Phase of Trial: Phase III/IV

Latest Information Update: 24 Jul 2017

At a glance

  • Drugs Alteplase (Primary)
  • Indications Embolism and thrombosis; Hypertension; Stroke
  • Focus Therapeutic Use
  • Acronyms ENCHANTED
  • Most Recent Events

    • 24 Jul 2017 Results of post hoc subgroup analysis (n=3220) assessing effect of renal dysfuction on outcomes and interaction with low versus standard dose alteplase, published in the Stroke Journal.
    • 15 Jun 2017 Results (n=3285) published in the Stroke
    • 12 Dec 2016 Planned End Date changed from 1 Dec 2016 to 1 Feb 2019.
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