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The ATOMIC Study: A Multicenter, Open-label, Randomized, Duration Finding Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Following Oral Administration of PSI-7977 in Combination With Pegylated Interferon and Ribavirin in Treatment-Naive Patients With Chronic HCV Infection Genotype 1,4, 5, or 6.

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Trial Profile

The ATOMIC Study: A Multicenter, Open-label, Randomized, Duration Finding Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Following Oral Administration of PSI-7977 in Combination With Pegylated Interferon and Ribavirin in Treatment-Naive Patients With Chronic HCV Infection Genotype 1,4, 5, or 6.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 14 Jan 2020

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At a glance

  • Drugs Sofosbuvir (Primary) ; Peginterferon; Peginterferon alfa-2a; Ribavirin
  • Indications Hepatitis C
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms ATOMIC
  • Sponsors Gilead Sciences

    • Most Recent Events

    • 19 Mar 2013 Results published in the Lancet.
    • 13 Nov 2012 Status changed from active, no longer recruiting to completed.
    • 19 Apr 2012 Interim data from this trial have been presented at the 47th Annual Meeting of the European Association for the Study of the Liver (EASL), according to a Gilead Sciences media release.
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