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Phase I Study of Z-Endoxifen as a Hormonal Therapy for Breast Cancer

Trial Profile

Phase I Study of Z-Endoxifen as a Hormonal Therapy for Breast Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 06 Nov 2023

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At a glance

  • Drugs Endoxifen (Primary)
  • Indications Advanced breast cancer
  • Focus Adverse reactions; First in man
  • Most Recent Events

    • 17 Sep 2021 Results (n=80) assessing the population pharmacokinetics (PK) of Z-endoxifen in patients with treatment-refractory gynecologic malignancies, desmoid tumors or hormone receptor-positive solid tumors from Mayo Clinic (NCT01327781) and National Cancer Inst (NCI, NCT01273168) trials, presented at the 2021 American College of Clinical Pharmacology Annual Meeting.
    • 30 Aug 2017 Results published in the Journal of Clinical Oncology
    • 06 Jun 2017 Results assessing tumor and circulating cell free (cf) DNA mutations, presented at the 53rd Annual Meeting of the American Society of Clinical Oncology.
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