Effects of clarithromycin, a cytochrome P450 3A4 inhibitor, on the pharmacokinetics and pharmacodynamics of oxycodone in young and elderly volunteers

Trial Profile

Effects of clarithromycin, a cytochrome P450 3A4 inhibitor, on the pharmacokinetics and pharmacodynamics of oxycodone in young and elderly volunteers

Completed
Phase of Trial: Phase IV

Latest Information Update: 10 May 2011

At a glance

  • Drugs Oxycodone (Primary) ; Clarithromycin
  • Indications Cancer pain; Helicobacter pylori infections; Neuropathic pain; Postoperative pain; Skin and soft tissue infections
  • Focus Pharmacodynamics; Pharmacogenomic; Pharmacokinetics
  • Most Recent Events

    • 10 May 2011 New trial record
    • 19 Apr 2011 Results published in the Journal of Clinical Psychopharmacology.
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