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A Double Blind Placebo-Controlled Trial of Eflornithine and Sulindac to Prevent Recurrence of High Risk Adenomas and Second Primary Colorectal Cancers in Patients With Stage 0-III Colon or Rectal Cancer, Phase III - Preventing Adenomas of the Colon With Eflornithine and Sulindac (PACES)

Trial Profile

A Double Blind Placebo-Controlled Trial of Eflornithine and Sulindac to Prevent Recurrence of High Risk Adenomas and Second Primary Colorectal Cancers in Patients With Stage 0-III Colon or Rectal Cancer, Phase III - Preventing Adenomas of the Colon With Eflornithine and Sulindac (PACES)

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 22 Mar 2024

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At a glance

  • Drugs Eflornithine (Primary) ; Sulindac
  • Indications Colorectal cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms PACES
  • Most Recent Events

    • 04 Oct 2023 Status changed from recruiting to active, no longer recruiting.
    • 28 Jun 2023 According to a Panbela Therapeutics media release, trial passed a single planned futility analysis and will continue as planned.
    • 25 Apr 2022 Planned End Date changed from 1 Jul 2029 to 1 Feb 2032.
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