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A First Time in Human, Single Blind, Randomized, Placebo-controlled,Dose Escalating Crossover Study to Evaluate the Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Parameters of Single Doses of GSK2330672 in Healthy Volunteers

Trial Profile

A First Time in Human, Single Blind, Randomized, Placebo-controlled,Dose Escalating Crossover Study to Evaluate the Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Parameters of Single Doses of GSK2330672 in Healthy Volunteers

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 23 Aug 2022

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At a glance

  • Drugs Linerixibat (Primary)
  • Indications Cholestasis; Primary biliary cirrhosis; Pruritus; Type 2 diabetes mellitus
  • Focus Adverse reactions
  • Sponsors GSK
  • Most Recent Events

    • 26 Jun 2022 Results from three Phase 1 studies 114985,116511, 205808 and from patients with PBC in two Phase 2 stud, 201000 and other study, presented at The International Liver Congress 2022
    • 25 Jun 2013 Results presented at the 73rd Annual Scientific Sessions of the American Diabetes Association.
    • 13 Oct 2011 Actual end date (October 2011) added as reported by ClinicalTrials.gov.
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