A Phase I, 2-panel, Open-label, Randomized, Cross-over Trial in Healthy Subjects to Investigate the Effect of TMC435 at Steady-state on the Pharmacokinetics of the Immunosuppressants Cyclosporine and Tacrolimus.
Phase of Trial: Phase I
Latest Information Update: 13 Nov 2012
At a glance
- Drugs Simeprevir (Primary) ; Ciclosporin; Tacrolimus
- Indications Hepatitis C; Liver transplant rejection
- Focus Pharmacodynamics; Pharmacokinetics
- Sponsors Janssen R&D Ireland
- 01 Oct 2012 Results will be presented at the 63nd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) according to a Medivir media release.
- 10 Jan 2012 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.
- 23 Dec 2011 Actual patient number is 29 according to ClinicalTrials.gov.
Most Recent Events
Table of Contents
- At a glance
- Trial Overview
- Trial Details
- Trial Centres
- Trial History