A double-blind randomized controlled trial comparing 0.75mg of Palonosetron with 1mg of Granisetron for the control of highly emetogenic chemotherapy-induced emesis.

Trial Profile

A double-blind randomized controlled trial comparing 0.75mg of Palonosetron with 1mg of Granisetron for the control of highly emetogenic chemotherapy-induced emesis.

Completed
Phase of Trial: Phase III

Latest Information Update: 29 Jun 2016

At a glance

  • Drugs Granisetron (Primary) ; Palonosetron (Primary) ; Aprepitant; Dexamethasone
  • Indications Chemotherapy-induced nausea and vomiting
  • Focus Therapeutic Use
  • Acronyms TRIPLE
  • Most Recent Events

    • 29 Jun 2016 Primary endpoint, (Complete control of nausea and vomiting) has not been met, according to a results published in the Annals of Oncology.
    • 29 Jun 2016 Results published in the Annals of Oncology
    • 23 Jan 2012 New trial record
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