A Randomized, Double-blind, Placebo-controlled, Phase 3 Study of Brentuximab Vedotin and CHP (A+CHP) Versus CHOP in the Frontline Treatment of Patients With CD30-positive Mature T-cell Lymphomas

Trial Profile

A Randomized, Double-blind, Placebo-controlled, Phase 3 Study of Brentuximab Vedotin and CHP (A+CHP) Versus CHOP in the Frontline Treatment of Patients With CD30-positive Mature T-cell Lymphomas

Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 30 Dec 2017

At a glance

  • Drugs Brentuximab vedotin (Primary) ; Cyclophosphamide; Doxorubicin; Prednisone; Vincristine
  • Indications Adult T-cell leukaemia-lymphoma; Anaplastic large cell lymphoma; Non-Hodgkin's lymphoma; Peripheral T-cell lymphoma; T cell lymphoma
  • Focus Registrational; Therapeutic Use
  • Acronyms ECHELON-2
  • Sponsors Seattle Genetics
  • Most Recent Events

    • 14 Dec 2017 Planned primary completion date changed from 1 Dec 2017 to 1 Dec 2018.
    • 09 Feb 2017 According to a Seattle Genetics media release, top-line data anticipated in 2018 (previously expected in the 2017 to 2018 timeframe).
    • 08 Nov 2016 According to Seattle Genetics media release, additional four-year follow-up data from this trial will be presented in a poster presentation at the 2016 ASH Annual Meeting.
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