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A Phase I/II, Randomized, Study for Diabetic Macular Edema Using 0.3mg Ranibizumab Combined With Targeted PRP Monthly for 4 Months,Then PRN vs. 0.3mg Ranibizumab 4 Months Monotherapy, Then as Needed(DME-AntiVEgf) DAVE

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Trial Profile

A Phase I/II, Randomized, Study for Diabetic Macular Edema Using 0.3mg Ranibizumab Combined With Targeted PRP Monthly for 4 Months,Then PRN vs. 0.3mg Ranibizumab 4 Months Monotherapy, Then as Needed(DME-AntiVEgf) DAVE

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 29 Mar 2023

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At a glance

  • Drugs Ranibizumab (Primary)
  • Indications Diabetic macular oedema
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms DAVE

    • Most Recent Events

    • 01 Mar 2023 Results of post hoc analysis assessing relationship between baseline retinal non-perfusion area (NPA) and retinal vascular bed area (RVBA) on ultra-wide field fluorescein angiography (UWF FA) and long-term response to intravitreal ranibizumab therapy in diabetic macular oedema published in the Eye
    • 31 Aug 2018 Status changed from active, no longer recruiting to completed.
    • 01 Aug 2017 Results assessing distribution of nonperfusion area from 29 treatment-naive patients of this trial published in the American Journal of Ophthalmology
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