Trial Profile
Phase III randomized sequential open-label study to evaluate the efficacy and safety of sorafenib followed by pazopanib versus pazopanib followed by sorafenib in the treatment of advanced / metastatic renal cell carcinoma (SWITCH 2)
Status:
Completed
Phase of Trial:
Phase III
Latest Information Update: 20 Oct 2022
Price :
$35
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At a glance
- Drugs Pazopanib (Primary) ; Sorafenib (Primary)
- Indications Renal cancer
- Focus Therapeutic Use
- Acronyms SWITCH-2; SWITCH-II
- 06 Dec 2018 Results published in the European Journal of Cancer
- 12 Sep 2017 Primary endpoint (To evaluate if progression-free survival from randomization to progression or death during second-line therapy (Total PFS) of sorafenib followed by pazopanib is non-inferior compared to pazopanib followed by sorafenib) has not been met, aaccording to the results presented at the 42nd European Society for Medical Oncology Congress.
- 12 Sep 2017 Results presented at the 42nd European Society for Medical Oncology Congress.