A Double-Blind, Placebo-Controlled Parallel-Group Study in Preclinical PSEN1 E280A Mutation Carriers Randomized to Crenezumab or Placebo, and in Nonrandomized, Placebo-Treated Noncarriers From the Same Kindred, to Evaluate the Efficacy and Safety of Crenezumab in the Treatment of Autosomal-Dominant Alzheimer's Disease

Trial Profile

A Double-Blind, Placebo-Controlled Parallel-Group Study in Preclinical PSEN1 E280A Mutation Carriers Randomized to Crenezumab or Placebo, and in Nonrandomized, Placebo-Treated Noncarriers From the Same Kindred, to Evaluate the Efficacy and Safety of Crenezumab in the Treatment of Autosomal-Dominant Alzheimer's Disease

Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 17 Apr 2017

At a glance

  • Drugs Crenezumab (Primary)
  • Indications Alzheimer's disease
  • Focus Therapeutic Use
  • Sponsors Genentech
  • Most Recent Events

    • 07 Jun 2017 Biomarkers information updated
    • 12 Apr 2017 Status changed from recruiting to active, no longer recruiting.
    • 23 Dec 2013 Treatment has been initiated in the first enrolled patients, according to an AC Immune media release.
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