Effects of Extended Release Methylnaltrexone Bromide (150 mg b.i.d.) in Comparison to Extended Release Naloxone Hydrochloride (20 mg b.i.d.) on Loperamide-induced Delay of the Oro-cecal, Whole-gut and Colon Transit Time in Healthy Subjects.
Phase of Trial: Phase I
Latest Information Update: 17 May 2012
At a glance
- Drugs Methylnaltrexone bromide (Primary) ; Loperamide; Naloxone; Sulfasalazine
- Indications Constipation
- Focus Pharmacodynamics; Pharmacokinetics
- 17 May 2012 New trial record