An Open Label Positron Emission Tomography Study in Healthy Male Subjects to Investigate Brain PDE4 Engagement, Pharmacokinetics and Safety of Single Oral Doses of GSK356278, Using 11C-(R)-Rolipram as a PET Ligand(s)

Trial Profile

An Open Label Positron Emission Tomography Study in Healthy Male Subjects to Investigate Brain PDE4 Engagement, Pharmacokinetics and Safety of Single Oral Doses of GSK356278, Using 11C-(R)-Rolipram as a PET Ligand(s)

Completed
Phase of Trial: Phase I

Latest Information Update: 24 Jun 2017

At a glance

  • Drugs GSK 356278 (Primary)
  • Indications Huntington's disease
  • Focus Pharmacodynamics; Pharmacokinetics
  • Most Recent Events

    • 24 May 2012 New trial record
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