A Randomized, Multicenter, Open-Label, Two-Arm, Phase III Neoadjuvant Study Evaluating Trastuzumab Emtansine Plus Pertuzumab Compared With Chemotherapy Plus Trastuzumab and Pertuzumab for Patients With HER2-Positive Breast Cancer

Trial Profile

A Randomized, Multicenter, Open-Label, Two-Arm, Phase III Neoadjuvant Study Evaluating Trastuzumab Emtansine Plus Pertuzumab Compared With Chemotherapy Plus Trastuzumab and Pertuzumab for Patients With HER2-Positive Breast Cancer

Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 29 Sep 2017

At a glance

  • Drugs Trastuzumab emtansine (Primary) ; Carboplatin; Docetaxel; Pertuzumab; Trastuzumab
  • Indications Early breast cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms KRISTINE
  • Sponsors Roche
  • Most Recent Events

    • 29 Sep 2017 Planned End Date changed from 1 Jan 2018 to 31 Mar 2018.
    • 07 Jun 2016 Results assessing efficacy of trastuzumab emtansine in early breast cancer patients presented at the 52nd Annual Meeting of the American Society of Clinical Oncology.
    • 02 Jul 2015 Status changed from recruiting to active, no longer recruiting as reported by ClinicalTrials.gov.
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