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A Randomized, Double-Blind, Placebo-Controlled Phase 1b/2 Study of LY2228820, a p38MAPK Inhibitor, plus Gemcitabine and Carboplatin versus Gemcitabine and Carboplatin for Women with Platinum-Sensitive Ovarian Cancer

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Trial Profile

A Randomized, Double-Blind, Placebo-Controlled Phase 1b/2 Study of LY2228820, a p38MAPK Inhibitor, plus Gemcitabine and Carboplatin versus Gemcitabine and Carboplatin for Women with Platinum-Sensitive Ovarian Cancer

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 09 Dec 2019

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At a glance

  • Drugs Ralimetinib (Primary) ; Carboplatin; Gemcitabine
  • Indications Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Eli Lilly and Company

    • Most Recent Events

    • 29 Nov 2019 Results published in the Gynecologic Oncology.
    • 04 Jun 2019 India was planned location as per European Clinical Trials Database.
    • 04 Jun 2019 Primary endpoint has been met. (Phase 2: Progression-free Survival (PFS) in Participants Treated With LY2228820 Plus Gemcitabine and Carboplatin Versus Placebo Plus Gemcitabine and Carboplatin) as per results presented at the 55th Annual Meeting of the American Society of Clinical Oncology.
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