A Phase 3 Study to Evaluate the Efficacy and Safety of Induction and Maintenance Regimens of Brodalumab Compared With Placebo and Ustekinumab in Subjects With Moderate to Severe Plaque Psoriasis: AMAGINE-2

Trial Profile

A Phase 3 Study to Evaluate the Efficacy and Safety of Induction and Maintenance Regimens of Brodalumab Compared With Placebo and Ustekinumab in Subjects With Moderate to Severe Plaque Psoriasis: AMAGINE-2

Discontinued
Phase of Trial: Phase III

Latest Information Update: 20 Jul 2017

At a glance

  • Drugs Brodalumab (Primary) ; Ustekinumab
  • Indications Plaque psoriasis
  • Focus Registrational; Therapeutic Use
  • Acronyms AMAGINE-2
  • Sponsors Amgen
  • Most Recent Events

    • 20 Jul 2017 According to a LEO Pharma media release, European Commission has granted marketing authorisation for Kyntheum (brodalumab), a new biologic for the treatment of moderate-to-severe plaque psoriasis in adults within the European Union who are candidates for systemic therapy.
    • 08 Jun 2017 Planned location also included Germany, Turkey and United Kingdom as per European Clinical Trials Database.
    • 19 May 2017 According to an AstraZeneca media release, the CHMPs positive opinion on brodalumab will now be reviewed by the European Commission and the final decision is applicable to all EU and European Economic Area countries (Iceland, Liechtenstein and Norway).
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