Randomized comparison of two different treatment concepts in newly diagnosed acute promyelocytic leukemia (APL). A randomized study for comparison of the effects of ATRA and intensified double induction therapy incorporating high dose ara-C followed by TAD consolidation and cyclic maintenance therapy (AMLCG concept) and induction therapy with ATRA and idarubicin (AIDA) followed by three anthracyclin/ATRA- based consloidation courses and maintenance therapy (PETHEMA conzept).
Phase of Trial: Phase III
Latest Information Update: 10 Sep 2016
At a glance
- Drugs Tretinoin (Primary) ; Cyclophosphamide; Cytarabine; Cytarabine; Daunorubicin; Idarubicin; Mercaptopurine; Methotrexate; Mitoxantrone; Tioguanine
- Indications Acute promyelocytic leukaemia
- Focus Therapeutic Use
- 04 Sep 2012 New trial record