Efficacy and safety of fixed-dose combination Perindopril 5 mg / Indapamide 1.25 mg / Amlodipine 5 mg versus Perindopril 5 mg / Indapamide 1.25 mg single pill in patients with uncontrolled essential hypertension after 1 month of treatment by Perindopril 5 mg / Indapamide 1.25 mg single pill with conditional titration based on blood pressure control up to Perindopril 10 mg/ Indapamide 2.5 mg / Amlodipine 10 mg. An international, multicentre, randomised, double blind, 4-month superiority study.

Trial Profile

Efficacy and safety of fixed-dose combination Perindopril 5 mg / Indapamide 1.25 mg / Amlodipine 5 mg versus Perindopril 5 mg / Indapamide 1.25 mg single pill in patients with uncontrolled essential hypertension after 1 month of treatment by Perindopril 5 mg / Indapamide 1.25 mg single pill with conditional titration based on blood pressure control up to Perindopril 10 mg/ Indapamide 2.5 mg / Amlodipine 10 mg. An international, multicentre, randomised, double blind, 4-month superiority study.

Completed
Phase of Trial: Phase III

Latest Information Update: 21 Sep 2015

At a glance

  • Drugs Amlodipine/indapamide/perindopril (Primary) ; Perindopril/indapamide
  • Indications Essential hypertension
  • Focus Registrational; Therapeutic Use
  • Sponsors Servier
  • Most Recent Events

    • 19 Sep 2015 Status changed from recruiting to completed, according to European Clinical Trials Database record.
    • 21 Dec 2013 Planned number of patients changed from 448 to 600 as reported by European Clinical Trials Database.
    • 30 Mar 2013 Planned End Date (13 Jul 2014) added as reported by European Clinical Trials Database.
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