A Phase I/II Study Afatinib/Carboplatin/Paclitaxel Induction Chemotherapy Followed By Standard Chemoradiation In HPV-Negative or High-risk HPV-Positive Locally Advanced Stage III/IVa/IVb HNSCC

Trial Profile

A Phase I/II Study Afatinib/Carboplatin/Paclitaxel Induction Chemotherapy Followed By Standard Chemoradiation In HPV-Negative or High-risk HPV-Positive Locally Advanced Stage III/IVa/IVb HNSCC

Completed
Phase of Trial: Phase I/II

Latest Information Update: 02 Feb 2017

At a glance

  • Drugs Afatinib (Primary) ; Carboplatin (Primary) ; Paclitaxel (Primary) ; Cisplatin
  • Indications Head and neck cancer
  • Focus Adverse reactions; Therapeutic Use
  • Most Recent Events

    • 26 Jan 2017 Status changed from active, no longer recruiting to completed.
    • 12 Oct 2016 Planned End Date changed from 1 Jan 2017 to 1 Jan 2019.
    • 15 Apr 2015 Status changed from recruiting to active, no longer recruiting as reported by ClinicalTrials.gov record.
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