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A Phase 1, Randomized, Double-blind, Placebo-Controlled, Dose-Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MEDI4893, an Extended Half-Life Human Monoclonal Antibody Against Staphylococcus Aureus Alpha Toxin, in Healthy Adult Subjects

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A Phase 1, Randomized, Double-blind, Placebo-Controlled, Dose-Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MEDI4893, an Extended Half-Life Human Monoclonal Antibody Against Staphylococcus Aureus Alpha Toxin, in Healthy Adult Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 20 Dec 2019

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At a glance

  • Drugs Suvratoxumab (Primary)
  • Indications Nosocomial pneumonia; Staphylococcal infections
  • Focus Adverse reactions; First in man
  • Sponsors MedImmune

    • Most Recent Events

    • 17 Oct 2016 Results published in the Antimicrobial Agents and Chemotherapy.
    • 21 Sep 2015 Results presented at the Joint 55th Interscience Conference on Antimicrobial Agents and Chemotherapy and 28th International Congress of Chemotherapy
    • 23 Jul 2014 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov record.

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