A single-arm, multicenter, nilotinib treatment-free remission study in patients with BCR-ABL1 positive Chronic Myelogenous Leukemia in chronic phase who have achieved durable minimal residual disease (MRD) status on first line nilotinib treatment

Trial Profile

A single-arm, multicenter, nilotinib treatment-free remission study in patients with BCR-ABL1 positive Chronic Myelogenous Leukemia in chronic phase who have achieved durable minimal residual disease (MRD) status on first line nilotinib treatment

Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 21 Jul 2017

At a glance

  • Drugs Nilotinib (Primary)
  • Indications Chronic myeloid leukaemia
  • Focus Registrational; Therapeutic Use
  • Acronyms ENESTFreedom
  • Sponsors Novartis
  • Most Recent Events

    • 14 Jul 2017 Status changed from recruiting to active, no longer recruiting.
    • 25 Jun 2017 96 weeks results (data cutoff, 31 Oct 2016) presented at the 22nd Congress of the European Haematology Association.
    • 23 Jun 2017 According to a Novartis media release, this study is ongoing with planned follow-up to evaluate the ability of patients to sustain remission for longer durations following discontinuation of Tasigna.
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