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A Randomized, Double-blind, Placebo-controlled, Parallel-group Proof of Concept Study to Evaluate the Effect of AFQ056 in Obsessive Compulsive Disorder (OCD) Patients Resistant to Selective Serotonin Reuptake Inhibitor (SSRI) Therapy

Trial Profile

A Randomized, Double-blind, Placebo-controlled, Parallel-group Proof of Concept Study to Evaluate the Effect of AFQ056 in Obsessive Compulsive Disorder (OCD) Patients Resistant to Selective Serotonin Reuptake Inhibitor (SSRI) Therapy

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Mavoglurant (Primary) ; Serotonin uptake inhibitors
  • Indications Obsessive-compulsive disorders
  • Focus Proof of concept; Therapeutic Use
  • Sponsors Novartis Pharmaceuticals
  • Most Recent Events

    • 02 Jan 2017 Primary endpoint of yale - brown obsessive compulsive scale (Y-BOCS) absolute change from baseline at week 17 has not been met, according to result published in the Advances in Therapy.
    • 02 Jan 2017 Results of interim analysis (n=50) published in the Advances in Therapy
    • 09 Jun 2016 Status changed from completed to discontinued at the time of the first Interim Analysis (IA) as the study did not meet its primary efficacy objective
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