A Pilot Study of Mitoxantrone in Combination With Clofarabine (MITCL) in Children, Adolescents and Young Adults (CAYA) With Refractory/Relapsed Acute Leukemia or High Grade Non-Hodgkin Lymphoma

Trial Profile

A Pilot Study of Mitoxantrone in Combination With Clofarabine (MITCL) in Children, Adolescents and Young Adults (CAYA) With Refractory/Relapsed Acute Leukemia or High Grade Non-Hodgkin Lymphoma

Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 03 Aug 2016

At a glance

  • Drugs Clofarabine (Primary) ; Mitoxantrone (Primary) ; Cytarabine; Dexrazoxane; Rituximab
  • Indications Acute lymphoblastic leukaemia; Acute myeloid leukaemia; Burkitt's lymphoma; Diffuse large B cell lymphoma; Non-Hodgkin's lymphoma
  • Focus Adverse reactions
  • Acronyms MITCL
  • Most Recent Events

    • 07 Jun 2016 Interim results of phase I part of this study (n=18) presented at the 52nd Annual Meeting of the American Society of Clinical Oncology
    • 20 Apr 2016 Interim results of phase I part of this study (n=17) presented at the 107th Annual Meeting of the American Association for Cancer Research
    • 08 Dec 2015 Results (n=15), presented at the 57th Annual Meeting and Exposition of the American Society of Hematology.
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