A Phase I Open-label, Dose-escalation Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of the PI3K Inhibitor WX-037, Given as a Single Agent and in Combination With the MEK Inhibitor WX-554, in Patients With Solid Tumors

Trial Profile

A Phase I Open-label, Dose-escalation Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of the PI3K Inhibitor WX-037, Given as a Single Agent and in Combination With the MEK Inhibitor WX-554, in Patients With Solid Tumors

Discontinued
Phase of Trial: Phase I

Latest Information Update: 01 Jul 2014

At a glance

  • Drugs WX 037 (Primary) ; WX 554 (Primary)
  • Indications Solid tumours
  • Focus Adverse reactions; Biomarker
  • Sponsors WILEX AG
  • Most Recent Events

    • 14 Apr 2014 Status changed from recruiting to discontinued, as reported in a Wilex media release.
    • 07 Aug 2013 Status changed from not yet recruiting to recruiting, according to a WILEX media release. The first patients have been enrolled and dosed.
    • 18 Jul 2013 According to the WILEX half-yearly financial report 2013, clinical development for WX-037 began in July 2013.
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