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A Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Study to Evaluate the Efficacy, Safety and Tolerability of Serelaxin When Added to Standard Therapy in Acute Heart Failure Patients

Trial Profile

A Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Study to Evaluate the Efficacy, Safety and Tolerability of Serelaxin When Added to Standard Therapy in Acute Heart Failure Patients

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 28 Jul 2023

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At a glance

  • Drugs Serelaxin (Primary)
  • Indications Acute heart failure
  • Focus Registrational; Therapeutic Use
  • Acronyms Relax-AHF-2
  • Sponsors Novartis Pharmaceuticals
  • Most Recent Events

    • 18 Jul 2023 Results of secondary analysis assessing if initiation of mineralocorticoid receptor antagonists prior to hospital discharge is associated with improved outcomes, published in the European Journal of Heart Failure.
    • 01 Jul 2023 Results (n=6318) assessing the effects of serelaxin on cardiovascular mortality at 180 days could be mediated by improvement in renal function, published in the Clinical Research in Cardiology.
    • 13 Mar 2023 Results assessing the role of mitral regurgitation in patients hospitalized for acute heart failure , published in the European Journal of Heart Failure
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