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A Phase 2 Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Trial of Linaclotide Administered Orally for 8 Weeks to Adult Outpatients With Opioid-Induced Constipation Receiving Chronic Opioid Treatment for Non-Cancer Pain

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Trial Profile

A Phase 2 Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Trial of Linaclotide Administered Orally for 8 Weeks to Adult Outpatients With Opioid-Induced Constipation Receiving Chronic Opioid Treatment for Non-Cancer Pain

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 06 May 2021

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At a glance

  • Drugs Linaclotide (Primary)
  • Indications Constipation
  • Focus Therapeutic Use
  • Sponsors Actavis; Forest Laboratories

    • Most Recent Events

    • 30 Nov 2015 According to an Ironwood Pharmaceuticals media release, positive top-line results are published.
    • 30 Nov 2015 According to an Ironwood Pharmaceuticals media release, primary endpoint (Change from baseline in the 8-week Spontaneous Bowel Movement (SBM) frequency rate (SBMs/week) during the Treatment Period) has been met.
    • 03 Nov 2015 According to an Ironwood Pharmaceuticals media release, data from this study is expected to be available in the fourth quarter of 2015.
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