Possible Drug Interaction Between Clopidogrel and Ranitidin or Omeprazole in Patients With Stable Coronary Heart Disease: a Comparative Study

Trial Profile

Possible Drug Interaction Between Clopidogrel and Ranitidin or Omeprazole in Patients With Stable Coronary Heart Disease: a Comparative Study

Completed
Phase of Trial: Phase IV

Latest Information Update: 11 Jun 2016

At a glance

  • Drugs Omeprazole (Primary) ; Ranitidine (Primary) ; Aspirin; Clopidogrel
  • Indications NSAID-induced gastrointestinal damage; Thromboembolism
  • Focus Pharmacodynamics
  • Most Recent Events

    • 11 Jun 2016 Primary endpoint has not been met. (Comparing Platelet Function of Patients on Dual Antiplatelet Therapy With ASA + Clopidogrel, Between the Groups Ranitidin and Omeprazole, Using VerifyNow Method.)
    • 11 Jun 2016 Results published in the American Journal of Cardiovascular Drugs
    • 12 May 2016 Study design has been changed from single group to double blind. Treatment arms changed from 1 to 2.
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