A prospective, multicentre phase II study comparing the efficacy and safety of second-line masitinib + lomustine vs masitinib + irinotecan in patients with relapsed glioblastoma multiforme

Trial Profile

A prospective, multicentre phase II study comparing the efficacy and safety of second-line masitinib + lomustine vs masitinib + irinotecan in patients with relapsed glioblastoma multiforme

Completed
Phase of Trial: Phase I/II

Latest Information Update: 25 Jun 2015

At a glance

  • Drugs Masitinib (Primary) ; Irinotecan; Lomustine
  • Indications Glioblastoma
  • Focus Therapeutic Use
  • Most Recent Events

    • 25 Jun 2015 According to an AB Science media release, this study did not pass the pre-planned statistical analysis to detect a superiority trend in overall survival between masitinib in combination with standard-of-care chemotherapy when compared against its relevant historical meta-analysis benchmark. Therefore, the indication will not be moved to phase III.
    • 25 Jun 2015 Status changed from recruiting to completed, according to an AB Science media release.
    • 04 Sep 2013 New trial record
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