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Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 3 Trial Of Fulvestrant (Faslodex (Registered)). With Or Without Pd-0332991 (Palbociclib) +/- Goserelin In Women With Hormone Receptor-positive, Her2-negative Metastatic Breast Cancer Whose Disease Progressed After Prior Endocrine Therapy

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Trial Profile

Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 3 Trial Of Fulvestrant (Faslodex (Registered)). With Or Without Pd-0332991 (Palbociclib) +/- Goserelin In Women With Hormone Receptor-positive, Her2-negative Metastatic Breast Cancer Whose Disease Progressed After Prior Endocrine Therapy

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 08 Apr 2024

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At a glance

  • Drugs Fulvestrant (Primary) ; Palbociclib (Primary) ; Goserelin
  • Indications Adenocarcinoma; Advanced breast cancer; HER2 negative breast cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms PALOMA-3
  • Sponsors Pfizer

    • Most Recent Events

    • 01 Feb 2024 Results appling a tumor regression-growth model to radiographic measurement data from 393 women with MBC enrolled in this study examining efficacy of palbociclib in disease that had progressed on previous endocrine therapy , published in the Breast Cancer Research and Treatment
    • 12 Jan 2023 Results published in the Breast Cancer Research
    • 10 Dec 2022 Results exploring the prognostic and predictive role of RBsig and CCNE1/RB1 in PALOMA-2 and PALOMA-3, presented at the 45th Annual San Antonio Breast Cancer Symposium
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