Phase 1b Study of Pharmacokinetic Interaction, Evaluating the Effect of a Single IV Infusion of GGF2 or Placebo on Midazolam Pharmacokinetics in Patients With Heart Failure
Phase of Trial: Phase I
Latest Information Update: 18 Mar 2017
At a glance
- Drugs Cimaglermin alfa (Primary) ; Midazolam
- Indications Acute coronary syndromes; Heart failure
- Focus Adverse reactions; Pharmacokinetics
- Sponsors Acorda Therapeutics
- 18 Mar 2017 Results (n=2) investigating cases of hepatotoxicity from two phase 1 trials (NCT01944683 and NCT01258387) meeting Hy's Law criteria, presented at the 118th Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics
- 12 Jul 2016 Status changed from active, no longer recruiting to completed.
- 21 Dec 2015 Planned End Date changed from 1 Nov 2015 to 1 Jul 2016 as reported by ClinicalTrials.gov record.