A Phase 3, Two-Part, Randomized, Double-Blind, Placebo-Controlled, Crossover Study With an Open-Label Period to Evaluate the Efficacy and Safety of Ivacaftor in Subjects With Cystic Fibrosis Who Have a Non-G551D CFTR Gating Mutation
Phase of Trial: Phase III
Latest Information Update: 03 Dec 2014
At a glance
- Drugs Ivacaftor (Primary)
- Indications Cystic fibrosis
- Focus Registrational; Therapeutic Use
- Acronyms KONNECTION
- Sponsors Vertex Pharmaceuticals
- 30 Jul 2014 According to a Vertex Pharmaceuticals media release, CHMP has given positive opinion for approval of ivacftor in treating cystic fibrosis in patients of who have one of the 8 non-G551D gating mutations.
- 27 Jun 2014 Results (part two of the trial) presented at the European Cystic Fibrosis Society Conference in June 2014.
- 27 Jun 2014 Results (Part one of the trial) published in the Vertex Pharmaceuticals Media Release.
Most Recent Events
Table of Contents
- At a glance
- Trial Overview
- Trial Details
- Trial Centres
- Trial History