A Multicenter Phase 1/2b Study of the Bruton's Tyrosine Kinase Inhibitor, Ibrutinib (PCI-32765), in Combination With Carfilzomib (Kyprolis) in Subjects With Relapsed or Relapsed and Refractory Multiple Myeloma

Trial Profile

A Multicenter Phase 1/2b Study of the Bruton's Tyrosine Kinase Inhibitor, Ibrutinib (PCI-32765), in Combination With Carfilzomib (Kyprolis) in Subjects With Relapsed or Relapsed and Refractory Multiple Myeloma

Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 03 Oct 2017

At a glance

  • Drugs Ibrutinib (Primary) ; Carfilzomib; Dexamethasone
  • Indications Multiple myeloma
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Pharmacyclics
  • Most Recent Events

    • 28 Sep 2017 Planned End Date changed from 1 Sep 2018 to 1 Sep 2019.
    • 28 Sep 2017 Planned primary completion date changed from 1 Feb 2018 to 1 Sep 2019.
    • 31 May 2016 Planned number of patients changed from 105 to 127.
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