A Double-Masked, Randomized, Active-Controlled Study of the Efficacy, Safety, and Tolerability of Intravitreal Administration of VEGF Trap-Eye (Intravitreal Aflibercept Injection [IAI]) in Patients With Macular Edema Secondary to Branch Retinal Vein Occlusion

Trial Profile

A Double-Masked, Randomized, Active-Controlled Study of the Efficacy, Safety, and Tolerability of Intravitreal Administration of VEGF Trap-Eye (Intravitreal Aflibercept Injection [IAI]) in Patients With Macular Edema Secondary to Branch Retinal Vein Occlusion

Completed
Phase of Trial: Phase III

Latest Information Update: 01 Feb 2016

At a glance

  • Drugs Aflibercept (Primary)
  • Indications Branch retinal vein occlusion
  • Focus Registrational; Therapeutic Use
  • Acronyms VIBRANT
  • Sponsors Regeneron Pharmaceuticals
  • Most Recent Events

    • 26 Jun 2015 According to a Regeneron Pharmaceuticals media release, Aflibercept received approval in Japan by the MHLW for the treatment of patients with macular edema secondary to retinal vein occlusion based on results of this study.
    • 26 Jun 2015 Results published in Santen Pharmaceutical media release.
    • 23 Jan 2015 According to a Regeneron Pharmaceuticals media release, aflibercept has been recommended for approval by the European CHMP for the treatment of visual impairment due to macular oedema secondary to central or branch retinal vein occlusion based on the results of this and another trial (see CT profile 700238571).
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