A Phase 2B, Randomized, Controlled, Multicenter, Open-Label Study of the Efficacy and Immune Response of GVAX Pancreas Vaccine (With Cyclophosphamide) and CRS 207 Compared to Chemotherapy or to CRS-207 Alone in Adults With Previously-Treated Metastatic Pancreatic Adenocarcinoma

Trial Profile

A Phase 2B, Randomized, Controlled, Multicenter, Open-Label Study of the Efficacy and Immune Response of GVAX Pancreas Vaccine (With Cyclophosphamide) and CRS 207 Compared to Chemotherapy or to CRS-207 Alone in Adults With Previously-Treated Metastatic Pancreatic Adenocarcinoma

Completed
Phase of Trial: Phase II

Latest Information Update: 04 May 2017

At a glance

  • Drugs CRS 207 (Primary) ; Tumour cell vaccine-GVAX (Primary) ; Cyclophosphamide
  • Indications Adenocarcinoma; Pancreatic cancer
  • Focus Therapeutic Use
  • Acronyms ECLIPSE
  • Sponsors Aduro BioTech
  • Most Recent Events

    • 25 Jan 2017 Status changed from active, no longer recruiting to completed.
    • 16 May 2016 Primary endpoint has not been met, (Overall survival in subjects receiving test treatments), according to an Aduro BioTech media release.
    • 08 Mar 2016 According to an Aduro BioTech media release, top-line results from this trial are expected in the second quarter of 2016.
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