A Phase 1b, Open-label Study to Assess the Safety and Tolerability of Tucatinib (ONT-380) Combined With Capecitabine and Trastuzumab, Alone and in Combination in HER2+ Metastatic Breast Cancer

Trial Profile

A Phase 1b, Open-label Study to Assess the Safety and Tolerability of Tucatinib (ONT-380) Combined With Capecitabine and Trastuzumab, Alone and in Combination in HER2+ Metastatic Breast Cancer

Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 16 Aug 2017

At a glance

  • Drugs Tucatinib (Primary) ; Capecitabine; Trastuzumab
  • Indications Advanced breast cancer; Male breast cancer
  • Focus Adverse reactions
  • Acronyms Triplet
  • Sponsors Cascadian Therapeutics
  • Most Recent Events

    • 10 Aug 2017 Planned End Date changed from 1 Jul 2017 to 1 Jul 2018.
    • 10 Aug 2017 Planned primary completion date changed from 1 Jul 2017 to 1 Jul 2018.
    • 05 Jan 2017 Updated results presented at the 2016 San Antonio Breast Cancer Symposium (SABCS), according to a Cascadian Therapeutics media release.
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