A phase I open-label, dose-escalation study to investigate the safety, pharmacokinetics, pharmacodynamics, immunogenicity and clinical activity of the antibody drug conjugate GSK2857916 in subjects with relapsed/refractory multiple myeloma and other advanced hematologic malignancies expressing BCMA

Trial Profile

A phase I open-label, dose-escalation study to investigate the safety, pharmacokinetics, pharmacodynamics, immunogenicity and clinical activity of the antibody drug conjugate GSK2857916 in subjects with relapsed/refractory multiple myeloma and other advanced hematologic malignancies expressing BCMA

Recruiting
Phase of Trial: Phase I

Latest Information Update: 14 Oct 2017

At a glance

  • Drugs GSK 2857916 (Primary)
  • Indications Haematological malignancies; Multiple myeloma
  • Focus Adverse reactions
  • Sponsors GlaxoSmithKline
  • Most Recent Events

    • 09 Oct 2017 Planned End Date changed from 3 Dec 2018 to 3 Jun 2019.
    • 09 Oct 2017 Planned primary completion date changed from 3 Dec 2018 to 3 Jun 2019.
    • 14 Sep 2017 Planned End Date changed from 12 Nov 2018 to 3 Dec 2018.
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