Trial Profile
A Multi-center, Open-label, Non-randomized, Phase I Dose Escalation Study of Regorafenib (BAY 73-4506) in Pediatric Subjects With Solid Malignant Tumors That Are Recurrent or Refractory to Standard Therapy
Status:
Active, no longer recruiting
Phase of Trial:
Phase I
Latest Information Update: 26 Oct 2023
Price :
$35
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At a glance
- Drugs Regorafenib (Primary) ; Irinotecan; Vincristine
- Indications Adenocarcinoma; Adrenal cancer; Astrocytoma; CNS cancer; Colon cancer; Ependymoma; Ewing's sarcoma; Glioblastoma; Glioma; Haemangioendothelioma; Hepatoblastoma; Medulloblastoma; Neuroblastoma; Oligodendroglioma; Osteosarcoma; Primitive neuroectodermal tumours; Rhabdomyosarcoma; Soft tissue sarcoma; Solid tumours; Wilms' tumour
- Focus Adverse reactions; Pharmacokinetics
- Sponsors Bayer; Bayer HealthCare
- 19 Oct 2023 Planned End Date changed from 28 Dec 2024 to 31 Mar 2024.
- 22 Aug 2023 Results(n=21, median age 10 years) published in the Clinical Cancer Research
- 08 Oct 2021 Planned End Date changed from 29 Dec 2023 to 28 Dec 2024.