A Phase 1b/2, Open Label, Randomized, Repeat Dose, Dose Escalation Study to Evaluate the Safety, Tolerability, Biological Activity, and Pharmacokinetics of ND-L02-s0201 Injection, A Vitamin A-coupled Lipid Nanoparticle Containing siRNA Against HSP47, in Subjects With Moderate to Extensive Hepatic Fibrosis (METAVIR F3-4).

Trial Profile

A Phase 1b/2, Open Label, Randomized, Repeat Dose, Dose Escalation Study to Evaluate the Safety, Tolerability, Biological Activity, and Pharmacokinetics of ND-L02-s0201 Injection, A Vitamin A-coupled Lipid Nanoparticle Containing siRNA Against HSP47, in Subjects With Moderate to Extensive Hepatic Fibrosis (METAVIR F3-4).

Completed
Phase of Trial: Phase I/II

Latest Information Update: 17 May 2017

At a glance

  • Drugs ND L02 s0201 (Primary)
  • Indications Fibrosis
  • Focus Adverse reactions
  • Acronyms METAVIR F3-4
  • Sponsors Nitto Denko
  • Most Recent Events

    • 08 Jun 2016 Status changed from active, no longer recruiting to completed.
    • 10 Dec 2015 Planned primary completion date changed from 1 Apr 2016 to 1 May 2016 as per ClinicalTrials.gov.
    • 10 Dec 2015 Status changed from recruiting to active, no longer recruiting as per ClinicalTrials.gov
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