A Phase 1 Study of the Oral TRK Inhibitor LOXO-101 in Adult Patients With Solid Tumors

Trial Profile

A Phase 1 Study of the Oral TRK Inhibitor LOXO-101 in Adult Patients With Solid Tumors

Recruiting
Phase of Trial: Phase I

Latest Information Update: 08 Dec 2017

At a glance

  • Drugs Larotrectinib (Primary)
  • Indications Small cell lung cancer; Solid tumours
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Sponsors Loxo Oncology
  • Most Recent Events

    • 04 Dec 2017 Planned number of patients changed from 108 to 90.
    • 18 Oct 2017 Top-line results from Independent Review Committee Assessment of Larotrectinib dataset were presented in a Loxo Oncology media release.
    • 06 Jun 2017 Results (data cut off: 31 Jan 2017, n=55) from NCT02122913, NCT02637687 and NCT02576431 studies, presented at the 53rd Annual Meeting of the American Society of Clinical Oncology.
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